Protagonist Therapeutics Inc. (PTGX)

$148.80

up-down-arrow $2.72 (1.86%)

As on 03-Sep-2026 16:00EDT

Market cap

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$9,339 Mln

Revenue (TTM)

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$282 Mln

P/E Ratio

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140.1

P/B Ratio

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11.5

Div. Yield

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0 %

Protagonist Therapeutics (PTGX) Share Price

Compare

High: Low: Return:

Max: Min: Median:

Max: Min: Median:

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Stock Range

Today’s Range

Low: 144.00 High: 149.49

52 Week Range

Low: 54.50 High: 160.81

Liquidityliquidity High

Low Moderate High

Fundamentals

  • Net Profit (TTM)Net Profit (TTM) information

    $0 Mln

  • ROEROE information

    0.1 %

  • ROCEROCE information

    -- %

  • Industry P/EIndustry P/E information

    --

  • EV/EBITDAEV/EBITDA information

    148.6

  • Debt to EquityDebt to Equity information

    0

  • Book ValueBook Value information

    $--

  • EPSEPS information

    $1

  • Face valueFace value information

    --

  • Shares outstandingShares outstanding information

    64,708,285

10 Years Aggregate

CFO

$-498.42 Mln

EBITDA

$-614.20 Mln

Net Profit

$-607.32 Mln

Performance

Company
YTD
1 Month
3 Months
1 Year
3 Years
5 Years
10 Years
Protagonist Therapeutics (PTGX)
70.4 8.9 59.6 152.8 96.7 24.6 28.5
BSE Sensex
-10.1 -2.5 2.0 -5.0 5.2 5.7 10.3
S&P Small-Cap 600#
-5.8 -5.3 -13.7 -6.3 5.3 3.0 5.5
As on 03-Sep-2026  |  #As on 26-Oct-2023
Company
2025
2024
2023
2022
2021
2020
2019
Protagonist Therapeutics (PTGX)
126.3 67.6 110.2 -68.1 69.6 186.0 4.8
S&P Small-Cap 600
4.0 7.0 13.9 -17.4 25.3 9.6 20.9
BSE Sensex
9.1 8.1 18.7 4.4 22.0 15.8 14.4

Essential Checks

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Is there a threat to the company's solvency?

Can creative accounting be detected through the financial numbers?

How did the company perform in the last one year?

Financials

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*All values are in ($ Mln)

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*All values are in ($ Mln)

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*All values are in ($ Mln)

Key Ratios

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5Y Avg -- 3Y Avg -- TTM --

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P/E Ratio

--

--Min --Median --Max

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P/B Ratio

--

--Min --Median --Max

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Earnings Yield (%)

--

Earnings Yield (%) = EBIT / Enterprise value

PEG Ratio

--

Price = Price / Earnings to growth ratio

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Peers

View Details
Company
Price ($) Market Cap ($ Mln) Revenue (TTM) Net Profit (TTM) OPM (%) ROE (%) P/E P/B
Protagonist Therapeutics (PTGX)
148.8 9,339.4 282.0 82.9 -28.6 11.4 140.1 11.5
86.5 11,993.9 669.5 -320.0 -0.8 -71.1 -- 26.9
271.1 16,261.1 1,054.4 755.9 5.7 -- 19 9.8
74.0 10,022.2 71.0 -894.0 -1,175.8 -- -- 60.3
59.1 13,491.7 2,435.9 860.6 31.0 43 17.4 7.4
110.8 11,957.0 1,663.7 413.6 36.3 430 30.9 84.5
371.5 10,402.8 440.5 241.5 33.4 18.7 44.1 7.8
542.6 12,332.1 1,283.9 -325.1 -19.0 -57.7 -- 24.0
593.4 16,765.1 2,782.3 491.5 21.1 110.1 35.2 39.3
355.2 9,625.4 0.0 -339.1 -- -30.6 -- 7.6

Shareholding Pattern

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About Protagonist Therapeutics (PTGX)

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and...  older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California. 

  • CEO, President, Secretary & Director

    Dr. Dinesh V. Patel Ph.D.

  • CEO, President, Secretary & Director

    Dr. Dinesh V. Patel Ph.D.

  • Headquarters

    Newark, CA

  • Website

    https://www.protagonist-inc.com

FAQs for Protagonist Therapeutics (PTGX)

The share price of Protagonist Therapeutics Inc (PTGX) is $148.80 (NASDAQ) as of 03-Sep-2026 16:00 EDT. Protagonist Therapeutics Inc (PTGX) has given a return of 96.74% in the last 3 years.

The P/E ratio of Protagonist Therapeutics Inc (PTGX) is 140.13 times as on 28-Aug-2026.
The P/B ratio of Protagonist Therapeutics Inc (PTGX) is 11.49 times as on 28-Aug-2026, a 122 premium to its peers’ median range of 5.18 times.


PE & PB ratio at the end of financial year.


Year P/E Ratio P/B Ratio
2025
-42.66
9.03
2024
9.31
3.80
2023
-17.95
4.21
2022
-4.35
2.49
2021
-13.12
5.49

The 52-week high and low of Protagonist Therapeutics Inc (PTGX) are Rs 160.81 and Rs 54.50 as of 04-Sep-2026.

Protagonist Therapeutics Inc (PTGX) has a market capitalisation of $ 9,339 Mln as on 28-Aug-2026. As per SEBI classification, it is a Small Cap company.

Before investing in Protagonist Therapeutics Inc (PTGX), assess your goals, risk tolerance, and if the company aligns with your long-term plan. Carefully review its business model, financials, and valuation. Avoid making decisions based on tips or short-term trends.

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