Protagonist Therapeutics Inc. (PTGX)

$152.01

up-down-arrow $3.72 (2.51%)

As on 12-Aug-2026 16:00EDT

Market cap

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$9,439 Mln

Revenue (TTM)

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$282 Mln

P/E Ratio

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143

P/B Ratio

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11.2

Div. Yield

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0 %

Protagonist Therapeutics (PTGX) Share Price

Compare

High: Low: Return:

Max: Min: Median:

Max: Min: Median:

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Stock Range

Today’s Range

Low: 147.33 High: 152.70

52 Week Range

Low: 53.49 High: 152.70

Liquidityliquidity High

Low Moderate High

Fundamentals

  • Net Profit (TTM)Net Profit (TTM) information

    $0 Mln

  • ROEROE information

    0.1 %

  • ROCEROCE information

    -- %

  • Industry P/EIndustry P/E information

    --

  • EV/EBITDAEV/EBITDA information

    145.1

  • Debt to EquityDebt to Equity information

    0

  • Book ValueBook Value information

    $--

  • EPSEPS information

    $1

  • Face valueFace value information

    --

  • Shares outstandingShares outstanding information

    64,708,285

10 Years Aggregate

CFO

$-498.42 Mln

EBITDA

$-614.20 Mln

Net Profit

$-607.32 Mln

Performance

Company
YTD
1 Month
3 Months
1 Year
3 Years
5 Years
10 Years
Protagonist Therapeutics (PTGX)
74.0 15.7 46.9 182.8 100.3 25.9 29.2
BSE Sensex*
-7.9 0.6 4.6 -2.8 6.1 7.3 10.7
S&P Small-Cap 600#
-5.8 -5.3 -13.7 -6.3 5.3 3.0 5.5
As on 12-Aug-2026  |  *As on 13-Aug-2026  |  #As on 26-Oct-2023
Company
2025
2024
2023
2022
2021
2020
2019
Protagonist Therapeutics (PTGX)
126.3 67.6 110.2 -68.1 69.6 186.0 4.8
S&P Small-Cap 600
4.0 7.0 13.9 -17.4 25.3 9.6 20.9
BSE Sensex
9.1 8.1 18.7 4.4 22.0 15.8 14.4

Essential Checks

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Is there a threat to the company's solvency?

Can creative accounting be detected through the financial numbers?

How did the company perform in the last one year?

Financials

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*All values are in ($ Mln)

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*All values are in ($ Mln)

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*All values are in ($ Mln)

Key Ratios

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5Y Avg -- 3Y Avg -- TTM --

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P/E Ratio

--

--Min --Median --Max

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P/B Ratio

--

--Min --Median --Max

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Earnings Yield (%)

--

Earnings Yield (%) = EBIT / Enterprise value

PEG Ratio

--

Price = Price / Earnings to growth ratio

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Peers

View Details
Company
Price ($) Market Cap ($ Mln) Revenue (TTM) Net Profit (TTM) OPM (%) ROE (%) P/E P/B
Protagonist Therapeutics (PTGX)
152.0 9,439.0 282.0 82.9 -28.6 11.4 143 11.2
87.3 12,381.0 669.5 -320.0 -0.8 -68.2 -- 26.6
84.5 8,920.5 42.2 -501.6 -1,217.0 -45.9 -- 6.9
75.6 10,421.8 71.0 -894.0 -1,175.8 -- -- 60.5
50.4 13,397.6 2,435.9 860.6 31.0 43 17 7.3
101.8 12,231.4 1,663.7 413.6 18.8 430 36.2 45.0
332.9 9,662.5 440.5 241.5 33.4 18.7 41 7.0
536.2 11,784.0 1,283.9 -325.1 -19.0 -57.7 -- 22.7
597.0 16,486.6 2,782.3 491.5 21.1 110.1 34.4 37.6
386.3 10,057.6 0.0 -339.1 -- -30.6 -- 6.1

Shareholding Pattern

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About Protagonist Therapeutics (PTGX)

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and...  older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California. 

  • CEO, President, Secretary & Director

    Dr. Dinesh V. Patel Ph.D.

  • CEO, President, Secretary & Director

    Dr. Dinesh V. Patel Ph.D.

  • Headquarters

    Newark, CA

  • Website

    https://www.protagonist-inc.com

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FAQs for Protagonist Therapeutics (PTGX)

The share price of Protagonist Therapeutics Inc (PTGX) is $152.01 (NASDAQ) as of 12-Aug-2026 16:00 EDT. Protagonist Therapeutics Inc (PTGX) has given a return of 100.32% in the last 3 years.

The P/E ratio of Protagonist Therapeutics Inc (PTGX) is 143.01 times as on 07-Aug-2026.
The P/B ratio of Protagonist Therapeutics Inc (PTGX) is 11.25 times as on 07-Aug-2026, a 111 premium to its peers’ median range of 5.32 times.


PE & PB ratio at the end of financial year.


Year P/E Ratio P/B Ratio
2025
-42.66
9.03
2024
9.31
3.80
2023
-17.95
4.21
2022
-4.35
2.49
2021
-13.12
5.49

The 52-week high and low of Protagonist Therapeutics Inc (PTGX) are Rs 152.70 and Rs 53.49 as of 13-Aug-2026.

Protagonist Therapeutics Inc (PTGX) has a market capitalisation of $ 9,439 Mln as on 07-Aug-2026. As per SEBI classification, it is a Small Cap company.

Before investing in Protagonist Therapeutics Inc (PTGX), assess your goals, risk tolerance, and if the company aligns with your long-term plan. Carefully review its business model, financials, and valuation. Avoid making decisions based on tips or short-term trends.

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