Alnylam Pharmaceuticals Inc. (ALNY)

$312.63

up-down-arrow $2.05 (0.66%)

As on 23-Apr-2026 10:40EDT

Market cap

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$41,317 Mln

Revenue (TTM)

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$3,714 Mln

P/E Ratio

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133.5

P/B Ratio

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52.4

Div. Yield

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0 %

Alnylam Pharmaceuticals (ALNY) Share Price

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Stock Range

Today’s Range

Low: 312.02 High: 315.83

52 Week Range

Low: 238.62 High: 495.55

Liquidityliquidity High

Low Moderate High

Fundamentals

  • Net Profit (TTM)Net Profit (TTM) information

    $314 Mln

  • ROEROE information

    0.7 %

  • ROCEROCE information

    12.9 %

  • Industry P/EIndustry P/E information

    --

  • EV/EBITDAEV/EBITDA information

    62.9

  • Debt to EquityDebt to Equity information

    1.6

  • Book ValueBook Value information

    $5.8

  • EPSEPS information

    $2.3

  • Face valueFace value information

    --

  • Shares outstandingShares outstanding information

    133,427,910

10 Years Aggregate

CFO

$-3,580.08 Mln

EBITDA

$-5,459.67 Mln

Net Profit

$-6,481.57 Mln

Performance

Company
YTD
1 Month
3 Months
1 Year
3 Years
5 Years
10 Years
Alnylam Pharmaceuticals (ALNY)
-21.4 0.1 -15.5 32.1 14.3 17.8 15.8
BSE Sensex
-8.3 4.2 -5.6 -2.4 9.2 10.1 11.6
S&P 100
1.3 10.1 2.5 37.6 22.9 13.3 14.2
As on 23-Apr-2026
Company
2025
2024
2023
2022
2021
2020
2019
Alnylam Pharmaceuticals (ALNY)
69.0 22.7 -19.5 40.1 30.5 12.9 58.0
S&P 100
18.7 29.0 30.8 -22.1 27.6 19.3 29.5
BSE Sensex
9.1 8.1 18.7 4.4 22.0 15.8 14.4

Essential Checks

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Is there a threat to the company's solvency?

Can creative accounting be detected through the financial numbers?

How did the company perform in the last one year?

Financials

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*All values are in ($ Mln)

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*All values are in ($ Mln)

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*All values are in ($ Mln)

Key Ratios

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5Y Avg -- 3Y Avg -- TTM --

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P/E Ratio

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P/B Ratio

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Earnings Yield (%)

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Earnings Yield (%) = EBIT / Enterprise value

PEG Ratio

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Price = Price / Earnings to growth ratio

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Peers

View Details
Company
Price ($) Market Cap ($ Mln) Revenue (TTM) Net Profit (TTM) OPM (%) ROE (%) P/E P/B
Alnylam Pharmaceuticals (ALNY)
312.6 41,317.3 3,713.9 313.8 11.2 73.3 133.5 52.4
143.1 31,186.3 606.4 -1,276.8 -196.7 -249.3 -- 42.2
74.6 12,506.7 944.0 -381.0 -31.6 -70.7 -- 25.6
161.3 29,945.3 16,310.0 1,360.0 14.2 21.6 21.9 4.4
54.7 21,304.7 1,944.0 -2,822.0 -142.4 -28.9 -- 2.5
131.4 13,402.6 2,860.5 478.6 24.1 16.4 28.5 4.1
754.6 79,350.1 14,342.9 4,504.9 36.8 14.9 18.1 2.5
23.3 19,500.6 0.0 -1,079.6 -- -206.1 -- 29.6
571.8 25,787.3 3,182.7 1,334.7 54.1 19.7 21.1 3.6
437.8 112,223.5 12,074.6 3,953.2 38.4 22.5 28.8 5.9

Shareholding Pattern

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About Alnylam Pharmaceuticals (ALNY)

Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally. The company offers ONPATTRO for hereditary...  transthyretin-mediated (hATTR) amyloidosis; AMVUTTRA for ATTR and hATTR amyloidosis; Leqvio for hypercholesterolemia; Qfitlia for hemophilia A or B; GIVLAARI for acute hepatic porphyria; and OXLUMO for primary hyperoxaluria type 1. It also develops a range of products in Phase 3 trial, such as Nucresiran for ATTR amyloidosis; Zilebesiran for hypertension; Cemdisiran for myasthenia gravis, paroxysmal nocturnal hemoglobinuria, and geographic atrophy; and Elebsiran for hepatitis D virus infections. In addition, the company is developing various products in Phase 2 trial, including Rapirosiran for metabolic dysfunction-associated steatohepatitis; ALN-ANG3 for diabetic kidney disease; ALN-4324 for type 2 diabetes mellitus; Mivelsiran for cerebral amyloid angiopathy, as well as in Phase 1 trial for Alzheimer's disease; and ALN-6400 for bleeding disorders. Further, it develops a range of products in Phase 1 trial, such as ALN-2232 for obesity and weight management; ALN-PNP for non-alcoholic fatty liver disease; ALN-APOC3 for dyslipidemia; ALN-CIDEB for metabolic dysfunction-associated steatohepatitis; ALN-HTT02 for Huntington's disease; ALN-5288 for Alzheimer's disease; ALN-SOD for SOD1 amyotrophic lateral sclerosis; ALN-SNCA for Parkinson's disease; AG-236 for polycythemia vera; ALN-CFB for paroxysmal nocturnal hemoglobinuria; ALN-BCAT for hepatocellular carcinoma; and ALN-4285, ALN-4915, and ALN-F1202 for healthy volunteers. The company has collaborations with Regeneron Pharmaceuticals, Inc.; Roche Holding AG; Sanofi S.A.; Novartis AG; PeptiDream, Inc; Dicerna Pharmaceuticals, Inc.; and Ionis Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Cambridge, Massachusetts.  Read more

  • CEO & Director

    Dr. Yvonne L. Greenstreet M.B.A., MBChB

  • CEO & Director

    Dr. Yvonne L. Greenstreet M.B.A., MBChB

  • Headquarters

    Cambridge, MA

  • Website

    https://www.alnylam.com

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FAQs for Alnylam Pharmaceuticals (ALNY)

The share price of Alnylam Pharmaceuticals Inc (ALNY) is $312.63 (NASDAQ) as of 23-Apr-2026 10:40 EDT. Alnylam Pharmaceuticals Inc (ALNY) has given a return of 14.31% in the last 3 years.

The P/E ratio of Alnylam Pharmaceuticals Inc (ALNY) is 133.47 times as on 17-Apr-2026.


PE & PB ratio at the end of financial year.


Year P/E Ratio P/B Ratio
2025
172.73
68.67
2024
-108.78
451.03
2023
-54.61
-108.97
2022
-25.90
-185.14
2021
-23.82
34.53

The 52-week high and low of Alnylam Pharmaceuticals Inc (ALNY) are Rs 495.55 and Rs 238.62 as of 23-Apr-2026.

Alnylam Pharmaceuticals Inc (ALNY) has a market capitalisation of $ 41,317 Mln as on 17-Apr-2026. As per SEBI classification, it is a Large Cap company.

Before investing in Alnylam Pharmaceuticals Inc (ALNY), assess your goals, risk tolerance, and if the company aligns with your long-term plan. Carefully review its business model, financials, and valuation. Avoid making decisions based on tips or short-term trends.

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