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Alnylam Pharmaceuticals (ALNY) Key Ratios

Stock Card factsheet share-fund-plan-icon

$238.27

up-down-arrow $-11.72 (-4.69%)

As on 15-Sep-2026 16:00EDT

Market cap

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$33,276 Mln

Revenue (TTM)

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$4,804 Mln

P/E Ratio

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43.1

P/B Ratio

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24.5

Div. Yield

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0 %

Key Ratios and Highlights

Growth Score (%) Quarterly Annual (TTM)
Particulars QoQ YoY 1-Year 3-Years 5-Years
Revenue 10.60 66.86 95.14 57.17 47.52
EBIT -20.54 4,629.30 581.89 47.04 28.04
Net Profit -20.15 348.19 353.22 40.27 23.83
EPS -20.16 332.80 337.57 38.93 22.63
Book Value -- -- 1,009.94 -- -7.90
Key Ratios (%) Average Annual (TTM)
Particulars3-Years5-YearsTTMDec-25Dec-24
EBIT-Margin info -4.02-37.9322.8115.50-10.48
Net Margin info ---116.9616.82----
Return on equity info 222.667.1075.4073.28362.29
Return on Capital info -14.54-36.11--18.29-22.73
Return on Assets info -4.00-13.5312.496.82-6.89
Debt to Equity (x) info ----0.751.6219.32

Profitability

View Detailed Peer Comparison

ROCE

--

--

Earning before interest and taxes / (Average net worth + Average total Debt) * 100

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
--
18.29
-22.73
-39.19
-82.33
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
ROE

75.40

Higher than Peers by 115.88

Profit after tax / Average Net worth * 100

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
75.40
73.28
362.29
232.40
-526.14
Peer Median
-40.48
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
ROA

12.49

Higher than Peers by 43.75

Profit after tax / Average Total assets * 100

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
12.49
6.82
-6.89
-11.94
-31.47
Peer Median
-31.26
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
EBIT Margin

22.81

Higher than Peers by 102.36

Operating profit (EBIT) / Net Sales * 100

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
22.81
15.50
-10.48
-17.08
-93.60
Peer Median
-79.54
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Net Margin

16.82

Higher than Peers by 105.57

Net profit / Total Income (Net sales plus other income) * 100

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
16.82
8.45
-12.37
-24.08
-132.85
Peer Median
-88.75
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Cash Profit Margin

--

--

(Net profit + Depreciation) / Gross Sales * 100

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
--
--
--
--
--
Peer Median
0.00
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.

Growth

View Detailed Peer Comparison

Revenue Growth

95.14

Higher than Peers by 40.36

Year on year growth in net sales

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
95.14
0.65
0.23
0.76
0.23
Peer Median
54.77
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
EBIT Growth

581.89

Higher than Peers by 582.69

Year on year growth in operating profit (EBIT)

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
581.89
344.47
24.59
67.84
-36.93
Peer Median
-0.80
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Net Profit Growth

353.22

Higher than Peers by 360.30

Year on year growth in profit after tax

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
353.22
212.79
36.82
61.08
-32.64
Peer Median
-7.08
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
EPS Growth

337.57

Higher than Peers by 323.13

Year on year growth in earnings per share

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
337.57
2.06
0.38
0.62
-0.29
Peer Median
14.44
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Book Value Growth

406.86

Higher than Peers by 416.78

Year on year growth in book value per share

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
406.86
--
--
--
--
Peer Median
-9.92
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.

Solvency

View Detailed Peer Comparison

Debt to Equity

0.75

--

Total debt / Net worth

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
0.75
1.62
19.32
-5.92
-8.34
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Short term debt to equity ratio

0.03

--

(Short term borrowings / Net worth)

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
0.03
0.06
0.62
-0.19
-0.27
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Current Ratio

3.05

Lower than Peers by 2.73

Current Assets / Current Liabilities and Provisions

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
3.05
2.76
2.78
3.08
3.51
Peer Median
5.79
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Quick Ratio

2.99

Lower than Peers by 2.66

(Current Assets - Inventory) / Current Liabilities and Provisions

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
2.99
2.71
2.71
2.99
3.34
Peer Median
5.65
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Interest Coverage

3.46

Higher than Peers by 5.44

Earning before interest and taxes (EBIT) / Interest Expenses

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
3.46
2.28
-1.66
-2.58
-6.23
Peer Median
-1.98
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.

Operating Efficiency

View Detailed Peer Comparison

Debtors to sales

19.00

Higher than Peers by 0.07

Debtors outstanding / Net Sales * 100

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
19.00
20.94
18.03
17.93
22.94
Peer Median
18.93
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Asset Turnover

0.74

Higher than Peers by 0.68

Sales / Average Total Assets

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
0.74
0.81
0.56
0.50
0.29
Peer Median
0.06
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Receivable days

--

--

Average Debtors / Sales * 365

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
--
58.17
59.55
56.51
76.85
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Inventory Days

--

--

Average Inventory / Sales * 365

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
--
43.48
94.68
128.32
232.94
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Payable days

--

--

Average Creditors / Cost of goods sold * 365

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
--
55.05
81.29
90.38
185.55
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Cash Conversion Cycle

--

--

Receivable Days + Inventory Days - Payable Days

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
--
46.59
72.95
94.46
124.23
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.

Valuation

View Detailed Peer Comparison

Price / Earnings

43.10

--

Current share price divided by earning per share in the last twelve months

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
43.10
172.73
-108.78
-54.61
-25.90
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Price / Book Value

24.46

Higher than Peers by 19.54

Current share price divided by book value per share in the latest financial year

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
24.46
68.67
451.03
-108.97
-185.14
Peer Median
4.92
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Dividend Yield

--

--

Dividend per share in the past twelve months divided by current share price

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
--
--
--
--
--
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
EV/EBITDA

28.12

--

Enterprise Value (Current Market Capitalisation + Total Debt - Cash & Equivalents) / Earnings before interest, taxes, depreciation and taxes (EBITDA)

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
28.12
83.24
-161.37
-88.71
-30.67
Peer Median
--
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
Market Cap

33,276

Higher than Peers by 33,144

Current Share price multiplied by latest total number of shares outstanding

Company Name
TTM
Dec-25
Dec-24
Dec-23
Dec-22
Alnylam Pharmaceuticals (ALNY)
33,276
--
--
--
--
Peer Median
132
--
--
--
--
*TTM (Trailing Twelve Months) data based on income statement of last 4 quarters and interim half yearly balance sheet.
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