Spero Therapeutics Inc. (SPRO)

$1.22

up-down-arrow $-0.01 (-0.81%)

As on 26-Aug-2026 16:00EDT

Market cap

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$70 Mln

Revenue (TTM)

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$43 Mln

P/E Ratio

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8.6

P/B Ratio

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1.6

Div. Yield

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0 %

Spero Therapeutics (SPRO) Share Price

Compare

High: Low: Return:

Max: Min: Median:

Max: Min: Median:

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Stock Range

Today’s Range

Low: 1.20 High: 1.23

52 Week Range

Low: 1.08 High: 3.08

Liquidityliquidity High

Low Moderate High

Fundamentals

  • Net Profit (TTM)Net Profit (TTM) information

    $0 Mln

  • ROEROE information

    0.2 %

  • ROCEROCE information

    -- %

  • Industry P/EIndustry P/E information

    --

  • EV/EBITDAEV/EBITDA information

    3.3

  • Debt to EquityDebt to Equity information

    0

  • Book ValueBook Value information

    $--

  • EPSEPS information

    $0.1

  • Face valueFace value information

    --

  • Shares outstandingShares outstanding information

    58,234,827

9 Years Aggregate

CFO

$-358.27 Mln

EBITDA

$-357.80 Mln

Net Profit

$-377.62 Mln

Performance

Company
YTD
1 Month
3 Months
1 Year
3 Years
5 Years
10 Years
Spero Therapeutics (SPRO)
-47.6 2.5 -55.8 -34.1 -1.6 -40.9 --
BSE Sensex*
-9.1 1.1 1.2 -4.8 5.8 6.6 10.7
S&P Small-Cap 600#
-5.8 -5.3 -13.7 -6.3 5.3 3.0 5.5
As on 26-Aug-2026  |  *As on 27-Aug-2026  |  #As on 26-Oct-2023
Company
2025
2024
2023
2022
2021
2020
2019
Spero Therapeutics (SPRO)
126.2 -29.7 -15.0 -89.2 -17.4 101.7 56.3
S&P Small-Cap 600
4.0 7.0 13.9 -17.4 25.3 9.6 20.9
BSE Sensex
9.1 8.1 18.7 4.4 22.0 15.8 14.4

Essential Checks

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Is there a threat to the company's solvency?

Can creative accounting be detected through the financial numbers?

How did the company perform in the last one year?

Financials

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*All values are in ($ Mln)

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*All values are in ($ Mln)

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*All values are in ($ Mln)

Key Ratios

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5Y Avg -- 3Y Avg -- TTM --

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P/E Ratio

--

--Min --Median --Max

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P/B Ratio

--

--Min --Median --Max

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Earnings Yield (%)

--

Earnings Yield (%) = EBIT / Enterprise value

PEG Ratio

--

Price = Price / Earnings to growth ratio

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Peers

View Details
Company
Price ($) Market Cap ($ Mln) Revenue (TTM) Net Profit (TTM) OPM (%) ROE (%) P/E P/B
Spero Therapeutics (SPRO)
1.2 70.5 43.0 7.4 -17.1 14.3 8.6 1.6
89.1 12,304.7 669.5 -320.0 -0.8 -71.1 -- 26.4
250.3 16,614.0 1,054.4 755.9 5.7 -- 19.4 10.1
79.2 10,682.6 71.0 -894.0 -1,175.8 -- -- 60.3
56.1 13,400.0 2,435.9 860.6 31.0 43 17 7.3
107.1 12,277.1 1,663.7 413.6 36.3 430 31.2 83.9
538.9 11,938.8 1,283.9 -325.1 -19.0 -57.7 -- 22.9
619.1 17,326.2 2,782.3 491.5 21.1 110.1 36.5 39.4
377.4 10,496.2 0.0 -339.1 -- -30.6 -- 7.6
151.5 9,985.8 282.0 82.9 -28.6 11.4 147 11.6

Shareholding Pattern

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About Spero Therapeutics (SPRO)

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates...  include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts. 

  • Co-Founder & Chairman of the Board

    Dr. Ankit Mahadevia M.D., MBA

  • Co-Founder & Chairman of the Board

    Dr. Ankit Mahadevia M.D., MBA

  • Headquarters

    Cambridge, MA

  • Website

    https://sperotherapeutics.com

FAQs for Spero Therapeutics (SPRO)

The share price of Spero Therapeutics Inc (SPRO) is $1.22 (NASDAQ) as of 26-Aug-2026 16:00 EDT. Spero Therapeutics Inc (SPRO) has given a return of -1.59% in the last 3 years.

The P/E ratio of Spero Therapeutics Inc (SPRO) is 8.64 times as on 21-Aug-2026.
The P/B ratio of Spero Therapeutics Inc (SPRO) is 1.59 times as on 21-Aug-2026, a 70 discount to its peers’ median range of 5.35 times.


PE & PB ratio at the end of financial year.


Year P/E Ratio P/B Ratio
2025
16.14
2.34
2024
-0.81
1.21
2023
3.42
0.73
2022
-1.82
1.11
2021
-5.73
5.83

The 52-week high and low of Spero Therapeutics Inc (SPRO) are Rs 3.08 and Rs 1.08 as of 27-Aug-2026.

Spero Therapeutics Inc (SPRO) has a market capitalisation of $ 70 Mln as on 21-Aug-2026. As per SEBI classification, it is a Small Cap company.

Before investing in Spero Therapeutics Inc (SPRO), assess your goals, risk tolerance, and if the company aligns with your long-term plan. Carefully review its business model, financials, and valuation. Avoid making decisions based on tips or short-term trends.

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